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Index > Protein center > Cav1(Gene name) > Rat
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  • Cav1 (Gene name),
  • Caveolin-1 (Protein name ),  CAV1_RAT from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    Cav1(Cav);
    Protein name:
    Caveolin-1;
    Alternative:

    Organism:
    Rat (Rattus norvegicus). 
    General Annotation
    Sub Unit:
    Homooligomer (By similarity). Interacts (via the N-terminus) with DPP4; the interaction is direct (By similarity). Interacts with SNAP25 and STX1A. Forms a stable heterooligomeric complex with CAV2 that targets to lipid rafts and drives caveolae formation. Interacts with BMX, BTK, CTNNB1, CDH1, GLIPR2, JUP and NOSTRIN.
    Function:
    Involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependent manner. May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity. Forms a stable heterooligomeric complex with CAV2 that targets to lipid rafts and drives caveolae formation. Recruits CTNNB1 to caveolar membranes and may regulate CTNNB1-mediated signaling through the Wnt pathway.
    Subcellular Location:
    Golgi apparatus membrane Peripheral membrane protein Cell membrane Peripheral membrane protein Membrane caveola Peripheral membrane protein Membrane raft Colocalized with DPP4 in membrane rafts. Potential hairpin-like structure in the membrane. Membrane protein of caveolae.
    Protein Attributes:
    Sequence length:
    178
    Sequence:
    50:
    MSGGKYVDSE | GHLYTVPIRE | QGNIYKPNNK | AMADEVNEKQ | VYDAHTKEID | 
    100:
    LVNRDPKHLN | DDVVKIDFED | VIAEPEGTHS | FDGIWKASFT | TFTVTKYWFY | 
    150:
    RLLSTIFGIP | MALIWGIYFA | ILSFLHIWAV | VPCIKSFLIE | IQCISRVYSI | 
    178:
    YVHTFCDPLF | EAIGKIFSNI | RISTQEEI
    3D Structure:
    N/A
    Predicted Eptitope:
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    EIAab Sequence  Vaild Sequence:
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    Related Databases
    String:
    Pfam:
    UniGene:
    Uniprot:
     
    FOR
    ELISA Kit for Rat Caveolin-1
    Cat.:
    E0214h
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    96T
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    ELISA Kit for Rat Caveolin-1
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    E0214r
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    96T
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    ELISA Kit for Rat Caveolin-1
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    E0214b
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    96T
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    ELISA Kit for Rat Caveolin-1
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    E0214m
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    96T
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    ELISA Kit for Rat Caveolin-1
    Cat.:
    E0214p
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    96T
    ELISA Kit for Rat Caveolin-1
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    E0214c
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    ELISA Kit for Rat Caveolin-1
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    ELISA Kit for Rat Caveolin-1
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    E0214d
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    Packing:
    96T
    CLIA Kit for Rat Caveolin-1
    Cat.:
    U0214p
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    96T
    CLIA Kit for Rat Caveolin-1
    Cat.:
    U0214r
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    96T
    CLIA Kit for Rat Caveolin-1
    Cat.:
    U0214b
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    96T
    CLIA Kit for Rat Caveolin-1
    Cat.:
    U0214m
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    Packing:
    96T
    CLIA Kit for Rat Caveolin-1
    Cat.:
    U0214c
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    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Rat Caveolin-1
    Cat.:
    U0214h
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    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Rat Caveolin-1
    Cat.:
    U0214d
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Rat Caveolin-1
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    Polyclonal Antibody for Rat Caveolin-1
    Cat.:
    P0214Rb-h
    Price:
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Rat Caveolin-1
    Polyclonal Antibody for Rat Caveolin-1
    Polyclonal Antibody for Rat Caveolin-1
    Cat.:
    P0214Rb-m
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    Packing:
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    Polyclonal Antibody for Rat Caveolin-1
    Polyclonal Antibody for Rat Caveolin-1
    Polyclonal Antibody for Rat Caveolin-1
    Polyclonal Antibody for Rat Caveolin-1
    Cat.:
    P0214Rb-r
    Price:
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    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Rat Caveolin-1
    Monoclonal Antibody for Rat Caveolin-1
    Monoclonal Antibody for Rat Caveolin-1
    Monoclonal Antibody for Rat Caveolin-1
    Monoclonal Antibody for Rat Caveolin-1
    Monoclonal Antibody for Rat Caveolin-1
    Monoclonal Antibody for Rat Caveolin-1
    Monoclonal Antibody for Rat Caveolin-1
    Protein for Rat Caveolin-1
    Protein for Rat Caveolin-1
    Protein for Rat Caveolin-1
    Protein for Rat Caveolin-1
    Protein for Rat Caveolin-1
    Protein for Rat Caveolin-1
    Protein for Rat Caveolin-1
    Protein for Rat Caveolin-1

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    References
    1. 1.
      "Immuno-electronmicroscopical identification of caveolin in rat adipocyte plasma membranes."
      Vinten J. , Voldstedlund M. , Carlsen J. , Christiansen K. , Clausen H. , Tranum-Jensen J.
      Submitted (1994-11) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
      tissue: Adipose tissue.
    2. 2.
      "ATP dependence of the SNARE/caveolin 1 interaction in the hippocampus."
      Magga J.M. , Kay J.G. , Davy A. , Poulton N.P. , Robbins S.M. , Braun J.E.A.
      Biochem. Biophys. Res. Commun.291:1232-1238(2002) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 1 AND 2);TISSUE SPECIFICITY;INTERACTION WITH SNAP25 AND SYNTAXIN
      strain: Sprague-Dawley.
      tissue: Brain.
    3. 3.
      "Co-localization and interaction of b0,+-type amino acid transporter 1 (BAT1) with caveolin-1 in rat kidney."
      Kwak J.O. , Kim H.W. , Jung S.M. , Song J.H. , Hong S.B. , Oh K.J. , Ko C.B. , Cha S.H.
      J. Nephrol.18:681-689(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUBCELLULAR LOCATION;TISSUE SPECIFICITY;INTERACTION WITH SLC7A9
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